• Home |
• Contact |
• Investigators |
• Careers |

• Profile
• Operations
• Research Programs
• Research Services
• Technology
• Locations

Recruitment, management, data systems, analysis and reporting

Site Management Syreon draws on its large international database of investigators to speed selection, recruitment, training, supervision and reimbursement, using Syreon ClinStream™ to reduce the costs and delays of investigator meetings and to permit continuous site support and performance evaluation. Syreon program managers maintain close collaboration with investigators and study personnel throughout the world while Syreon ClinStream™ streamlines patient screening, selection and randomization, enhancing the speed and accuracy of patient entry and preparing the sites for follow-on research. Biostatistics and Analysis Syreon provides full statistical support and trial analysis. Services range from detailed descriptive analyses to the complex multivariate regression, proportional hazards, time-dependent modelling and advanced pharmacokinetic analyses required to examine treatment roles and compare outcomes in real time. More specific services include detailed probabilistic decision models linking genetic predictors, clinical outcomes, health status, and economic variables for analysis of predictive value, cost-effectiveness or cost-utility. Sophisticated forecasting techniques permit emerging trends to be identified quickly and exploited using advanced adaptive designs. Monitoring Services Syreon offers a growing network of site monitoring services. Monitors are selected for their professional experience and interpersonal abilities, essential for effective interaction with site personnel, and adhere to stringent Syreon monitoring SOPs. They are fully trained in the use of Syreon's ClinStream™, skilled in the review of data and source document verification on site, and use standardized templates for all queries and reports.

Study Management Syreon provides all components of study design, project management, site management, investigator training, data management, study monitoring, on-line analysis and reporting. Syreon ClinStream™ enables fast and efficient site training and supervision, and links the study sponsor, investigators, advisory committee and data review board to ensure accurate and efficient study operation. Study modelling capabilities avoid expensive errors in design, and the ability to integrate studies in a tight, logical and continuous sequence with advanced design methods enables early trial interpretation for corporate decisions. Health Outcomes and Economics Syreon ClinStream™ measures the societal impact of treatment using both patient-reported outcomes and resource utilization measures. Health measures include an extensive library of patient-reported health preference, generic and disease-specific measures, while resource utilization is valued using country-specific cost vectors. Health and economic data are combined to create sophisticated models cost-effectiveness and cost-utility. Data Management Syreon ClinStream™ employs secure internet-based technologies for rapid and accurate data management. Automated electronic checks and detailed audit capabilities reduce entry errors and permit on-line data verification, while continuous site feedback enhances accuracy and efficiency. Data from all study sites is tracked electronically, enabling continuous reporting and analysis of metrics, and is coded using industry standard programs. Study information is available for the sponsor, monitors and advisory committees in real time to simplify record verification and ensure fast, safe and effective research. Medical Communications Syreon's experienced medical writers prepare study protocols, reports, abstracts, posters, presentation and scientific articles designed according to specific requirements for investigators and sponsors. Syreon ClinStream™ enables interim reports to be produced within days of critical events or queries, and final reports to be generated without delay following the last patient visit.